By Daniel Ladant,Joseph E. Alouf,Michel R. Popoff

This e-book describes the main achievements and discoveries correct to bacterial protein pollutants because the flip of the hot century illustrated by way of the invention of greater than fifty novel pollutants (many of them pointed out via genome screening). The institution of the third-dimensional crystal constitution of greater than 20 pollution through the related interval deals deeper wisdom of structure-activity relationships and offers a framework to appreciate how pollutants realize receptors, penetrate membranes and engage with and alter intracellular substrates.

* Edited by way of of the main extremely popular specialists within the box from the Institut Pasteur, France
* 14 fresh chapters devoted to insurance of ancient and normal elements of toxinology
* contains the key pollutants of either uncomplicated and scientific curiosity are defined intensive
* info utilized elements of poisons equivalent to treatment, vaccinology, and toolkits in cellphone biology
* Evolutionary and sensible points of bacterial pollutants evaluated and summarized
* Toxin functions in mobile biology presented
* treatment (cancer treatment, dystonias) discussed
* Vaccines (native and genetically engineered vaccines) featured
* pollution mentioned as organic guns, comprising chapters on anthrax, diphtheria, ricin etc.

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