By Naranjan S. Dhalla,Makoto Nagano,Bohuslav Ostadal
Molecular Defects in Cardiovascular Disease provides an in-depth dialogue of the molecular mechanisms underlying the genesis of cardiovascular defects and the results this has on present and rising distinct therapeutics. Divided into 3 sections, this ebook covers the medical foundations of our current figuring out in addition to the array of medical manifestations and their treatment. the 1st part covers Molecular Mechanisms of center ailment, with dialogue of the improvement of cardiovascular dysfunction. the remainder sections offer a extra scientific focus. the second one, Cardiac Hypertrophy and middle Failure bargains with metabolic derangements, Ca2+ dealing with, and subcellular home improvement. It illustrates the big variety of molecular defects that can function goals linked to the transition from cardiac hypertrophy to complicated center failure. The 3rd part, high blood pressure and Diabetes, offers molecular cause for the pathogenesis of high blood pressure and diabetic cardiomyopathy, in addition to highlighting the significance of hormones towards this end.
A helpful source for clinicians and researchers, this booklet elucidates the experimental foundation of the perform of cardiology. it's the end result of our advances within the figuring out of cardiovascular molecular biology and a blueprint for the efficacious use of specific therapies.
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